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Immune Support
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KPV

CAS 69679-21-8

C-terminal tripeptide of alpha-MSH. Anti-inflammatory activity via MC1R agonism and NF-kappaB suppression. Key compound for mucosal and systemic inflammation research.

≥99% Purity
White crystalline powder
MW 344.40 g/mol
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About This Product

KPV

Overview

KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-Melanocyte Stimulating Hormone (alpha-MSH 11-13), retaining the anti-inflammatory bioactivity of the parent peptide in a minimized scaffold. KPV acts primarily through MC1R (melanocortin receptor 1) and, independently, through direct intracellular NF-kappaB pathway modulation. Its small size enables excellent tissue penetration.

Research Applications

  • MC1R agonism and cAMP/PKA-mediated anti-inflammatory signaling
  • NF-kappaB pathway suppression and cytokine reduction research
  • Intestinal epithelial barrier function and mucosal inflammation studies
  • Structure-activity relationship (SAR) studies vs. full-length alpha-MSH

Quality Specifications

HPLC >=99%; LC-MS confirmed; endotoxin tested. Full CoA provided.

For Research Use Only. Not for human or veterinary use.

Technical Data

Product Specifications

Product NameKPV
CAS Number69679-21-8
Purity≥99% (by HPLC)
Molecular Weight344.40 g/mol
Molecular FormulaC15H28N4O5
AppearanceWhite crystalline powder
StorageStore at -20C desiccated. Stable >=36 months. Reconstituted: use within 14 days at 2-8C.
Available Sizes10mg · Custom
Storage

Store at -20C desiccated. Stable >=36 months. Reconstituted: use within 14 days at 2-8C.

Shelf Life

24 months from manufacture when stored properly.

Shipping

Cold-chain shipping with ice packs. Express delivery to 35+ countries.

HPLC Verified >=98% purity guaranteed
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KPV · CAS 69679-21-8

KPV
≥99% Purity · Immune Support

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