16-amino acid mitochondrial-derived peptide (MDP) encoded in the 12S rRNA of mitochondrial DNA. Key AMPK activator for mitochondrial function, metabolic flexibility, and aging research.
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid mitochondrial-derived peptide (MDP) encoded within the 12S ribosomal RNA gene of mitochondrial DNA. First characterized in 2015, MOTS-C activates AMPK (5-AMP-activated protein kinase), the master regulator of cellular energy sensing, and translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress.
HPLC >=99%; LC-MS confirmed; LAL endotoxin tested. Full CoA provided.
For Research Use Only. Not for human or veterinary use.
| Product Name | MOTS-C |
| CAS Number | 1627580-64-6 |
| Purity | ≥99% (by HPLC) |
| Molecular Weight | 2,174.59 g/mol |
| Molecular Formula | C100H160N36O25 |
| Appearance | White lyophilized powder |
| Storage | Store at -20C desiccated. Stable >=24 months. Reconstituted: use within 7 days at 2-8C. |
| Available Sizes | 10mg · Custom |
Store at -20C desiccated. Stable >=24 months. Reconstituted: use within 7 days at 2-8C.
24 months from manufacture when stored properly.
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MOTS-C · CAS 1627580-64-6
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