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Reta

CAS 2381272-90-6

Retatrutide (LY3437943) - triple GLP-1/GIP/glucagon receptor co-agonist for advanced multi-incretin metabolic signaling research.

≥99% Purity
White to off-white lyophilized powder
MW 5,209.82 g/mol
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About This Product

Reta

Overview

Retatrutide (LY3437943) is a first-in-class triple co-agonist simultaneously activating three incretin/glucagon receptors: GLP-1R, GIPR, and GcgR. This tri-agonist approach enables simultaneous study of all three major metabolic regulatory axes. The fatty acid-conjugated 39-mer peptide has a prolonged half-life suitable for once-weekly dosing in animal research models.

Research Applications

  • Triple GLP-1R/GIPR/GcgR co-agonism and signal integration studies
  • Comparative metabolic efficacy: mono vs. dual vs. triple agonism
  • Hepatic fat regulation and NASH preclinical models
  • Energy expenditure, thermogenesis, and glucagon biology

Quality Specifications

SPPS synthesis with fatty acid conjugation; HPLC >=99%; LC-MS confirmed; endotoxin tested. Full CoA provided.

For Research Use Only. Not for human or veterinary use.

Technical Data

Product Specifications

Product NameReta
CAS Number2381272-90-6
Purity≥99% (by HPLC)
Molecular Weight5,209.82 g/mol
Molecular FormulaC234H365N53O71
AppearanceWhite to off-white lyophilized powder
StorageStore at -20C desiccated. Stable >=24 months. Reconstituted: use within 7 days at 2-8C.
Available Sizes10mg · Custom
Storage

Store at -20C desiccated. Stable >=24 months. Reconstituted: use within 7 days at 2-8C.

Shelf Life

24 months from manufacture when stored properly.

Shipping

Cold-chain shipping with ice packs. Express delivery to 35+ countries.

HPLC Verified >=98% purity guaranteed
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Reta · CAS 2381272-90-6

Reta
≥99% Purity · Metabolic

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