Synthetic 43-amino acid Thymosin beta-4 fragment. Key actin-sequestering peptide for cell migration, angiogenesis, and anti-inflammatory pathway research.
TB-500 (Thymosin beta-4 fragment) is a 43-amino acid synthetic peptide derived from the naturally occurring 44-residue thymic peptide Thymosin beta-4. The bioactive LKKTET motif within Tb4 is responsible for G-actin sequestration, preventing actin polymerization. This activity underlies TB-500 roles in cell migration facilitation, wound healing signaling, angiogenesis promotion, and anti-inflammatory activity observed in preclinical models.
HPLC >=99%; LC-MS confirmed; LAL endotoxin <=1 EU/mg. Full CoA provided.
For Research Use Only. Not for human or veterinary use.
| Product Name | TB500 |
| CAS Number | 77591-33-4 |
| Purity | ≥99% (by HPLC) |
| Molecular Weight | 4,963.44 g/mol |
| Molecular Formula | C212H350N56O78S |
| Appearance | White to off-white lyophilized powder |
| Storage | Store at -20C desiccated. Stable >=24 months. Reconstituted: use within 7 days at 2-8C. |
| Available Sizes | 10mg · Custom |
Store at -20C desiccated. Stable >=24 months. Reconstituted: use within 7 days at 2-8C.
24 months from manufacture when stored properly.
Cold-chain shipping with ice packs. Express delivery to 35+ countries.
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TB500 · CAS 77591-33-4
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